Se ha realizado en nuestro entorno de pruebas una VTL Open Source sobre FC. Su implementación está basada en los trabajos previos sobre mhVTL y SCST .
Partiendo del escenario descrito en los post SCST 2 y SCST 3, donde se compiló un kernel vanilla y se le añadió el software SCST junto con los drivers de QLogic en modo target, configurado para que ofreciera a la SAN un disco virtual (VDISK). Se añade al servidor el proyecto mhVTL emulando una librería de cintas modelo Sun Storagetek L700 con un drive SDLT600 de QUANTUM, encargándose el módulo SCST de ofrecerlas a través de la HBA operando en modo Target.
El procedimiento de su implementación es:
1.- Crear entorno previo SCST descrito en el post SCST 2.
2.- Instalar proyecto mhVTL
3.- Configurar mhVTL
4.- Configurar SCST para dar visibilidad a los elementos de mhVTL por fibra.
2.- Instalar proyecto mhVTL
La instalación es idéntica a la descrita en el artículo VTL Open Source sobre iSCSI. Brevemente, descarga de las fuentes mhvtl en formato tar.gz desde la web del proyecto y realiza el siguiente procedimiento de instalación:
# useradd vtl
# passwd vtl
# mkdir /opt/mhvtl
# chown -Rf vtl:vtl /opt/mhvtl
# mkdir /etc/mhvtl
# chown -Rf vtl:vtl /etc/mhvtl
# cd /root/mhvtl-0.18-4
# make distclean
# cd kernel
# make
# make install
# cd ../
# make
# make install
3.- Configurar mhVTL
Edición del fichero /etc/mhvtl/device.conf para definir la librería y el drive:
# cat /etc/mhvtl/device.conf
VERSION: 4# VPD page format:
# <page #> <Length> <x> <x+1>… <x+n># NOTE: The order of records is IMPORTANT…
# The 'Unit serial number:' should be last (except for VPD data)
# i.e.
# Order is : Vendor ID, Product ID, Product Rev and serial number finally
# Zero, one or more VPD entries.
#
# Each 'record' is sperated by one (or more) blank lines.
# Each 'record' starts at column 1Library: 2 CHANNEL: 0 TARGET: 0 LUN: 0
Vendor identification: STK
Product identification: L700
Product revision level: 5500
Unit serial number: XYZZYDrive: 1 CHANNEL: 0 TARGET: 1 LUN: 0
Library ID: 2 Slot: 1
Vendor identification: QUANTUM
Product identification: SDLT600
Product revision level: 5500
Unit serial number: ZF7584364
Max density: 0x46
VPD: b0 04 00 02 01 00
Definir el contenido de la librería en el fichero /etc/mhvtl/library_contents:
# cat /etc/mhvtl/library_contents # Define how many tape drives you want in the vtl.. # The 'XYZZY_...' is the serial number assigned to # this tape device. Drive 1: ZF7584364 # Place holder for the robotic arm. Not really used. Picker 1: # Media Access Port # (mailslots, Cartridge Access Port, <insert your favourate name here>) # Again, define how many MAPs this vtl will contain. MAP 1: MAP 2: MAP 3: MAP 4: # And the 'big' on, define your media and in which slot contains media. # When the rc script is started, all media listed here will be created # using the default media capacity. Slot 1: 800843S3 Slot 2: 800844S3 Slot 3: 800845S3 Slot 4: 800846S3 Slot 5: 800847S3 Slot 6: 800848S3 Slot 7: 800849S3 Slot 8: 800850S3 Slot 9: 800851S3 Slot 10: 800852S3 Slot 11: 800853S3 Slot 12: 800854S3 Slot 13: 800855S3 Slot 14: 800856S3 Slot 15: 800857S3 Slot 16: 800858S3 Slot 17: 800859S3 Slot 18: 800860S3 Slot 19: 800861S3 Slot 20: 800862S3 Slot 21: Slot 22: Slot 23: Slot 24: Slot 25: Slot 26: Slot 27: Slot 28: Slot 29: Slot 30: Slot 31: CLN001L1 Slot 32: CLN002L1
4.- Configurar SCST para dar visibilidad a los elementos de mhVTL por fibra.
Levantar servicio mhVTL:
/etc/init.d/mhvtl start
Comprobación:
# lsscsi
[2:0:0:0] disk ATA WDC WD7500AACS-0 01.0 /dev/sda
[8:0:0:0] mediumx STK L700 5500 –
[8:0:1:0] tape QUANTUM SDLT600 5500 –
Se observan el VDISK (procedente de prueba anterior) y la librería STK L700 junto con el drive QUANTUM SDLT600 creados por mhVTL.
Se configura para que los dispositivos sean visibles por la HBA:
# echo "add 8:0:1:0 1" > /proc/scsi_tgt/groups/Default/devices
# echo "add 8:0:0:0 2" > /proc/scsi_tgt/groups/Default/devices
Y se pone en modo target el host asociado como interfaz en sysfs:
# echo “1″ >/sys/class/scsi_host/host7/target_mode_enabled
Comprobación:
# cat /sys/class/scsi_host/host7/active_mode
Target
# cat /proc/scsi_tgt/scsi_tgt
Device (host:ch:id:lun or name) Device handler
2:0:0:0 dev_disk
vm_disk vdisk_fileio
8:0:1:0 dev_tape
8:0:0:0 dev_changer
Desde el Host con W2K8 que opera en modo initiator se observan desde el administrador de dispositivos de la siguiente forma:
Se ha instalado la Utilidad OneCommand manager de Emulex con propósito de diagnóstico, la librería y el drive emulados se observan de la siguiente forma:
OneCommand Manager - Tape Drive
Para comprobar la conectividad del host con la VTL por FC se han usado las utilidades mtx en su versión para Windows:
- Estado de la librería:
c:\mtx>mtx.exe -f 3:0:0:2 status
Storage Changer 3:0:0:2:1 Drives, 36 Slots ( 4 Import/Export )
Data Transfer Element 0:Full (Storage Element 1 Loaded):VolumeTag = 800843S3Storage Element 1:Empty
Storage Element 2:Full :VolumeTag=800844S3
Storage Element 3:Full :VolumeTag=800845S3
Storage Element 4:Full :VolumeTag=800846S3
Storage Element 5:Full :VolumeTag=800847S3
Storage Element 6:Full :VolumeTag=800848S3
Storage Element 7:Full :VolumeTag=800849S3
Storage Element 8:Full :VolumeTag=800850S3
Storage Element 9:Full :VolumeTag=800851S3
Storage Element 10:Full :VolumeTag=800852S3
Storage Element 11:Full :VolumeTag=800853S3
Storage Element 12:Full :VolumeTag=800854S3
Storage Element 13:Full :VolumeTag=800855S3
Storage Element 14:Full :VolumeTag=800856S3
Storage Element 15:Full :VolumeTag=800857S3
Storage Element 16:Full :VolumeTag=800858S3
Storage Element 17:Full :VolumeTag=800859S3
Storage Element 18:Full :VolumeTag=800860S3
Storage Element 19:Full :VolumeTag=800861S3
Storage Element 20:Full :VolumeTag=800862S3
Storage Element 21:Empty
Storage Element 22:Empty
Storage Element 23:Empty
Storage Element 24:Empty
Storage Element 25:Empty
Storage Element 26:Empty
Storage Element 27:Empty
Storage Element 28:Empty
Storage Element 29:Empty
Storage Element 30:Empty
Storage Element 31:Full :VolumeTag=CLN001L1
Storage Element 32:Full :VolumeTag=CLN002L1
Storage Element 33 IMPORT/EXPORT:Empty
Storage Element 34 IMPORT/EXPORT:Empty
Storage Element 35 IMPORT/EXPORT:Empty
Storage Element 36 IMPORT/EXPORT:Empty
- Información de la librería:
c:\mtx>tapeinfo.exe -f 3:0:0:2
Product Type: Medium Changer
Vendor ID: 'STK '
Product ID: 'L700 '
Revision: '5500'
Attached Changer API: No
SerialNumber: 'XYZZY '
Ready: yes
- Información del drive:
c:\mtx>tapeinfo.exe -f Tape0
Product Type: Tape Drive
Vendor ID: 'QUANTUM '
Product ID: 'SDLT600 '
Revision: '5500'
Attached Changer API: No
SerialNumber: 'ZF7584364 '
MinBlock: 4
MaxBlock: 1048576
Ready: yes
BufferedMode: yes
Medium Type: Not Loaded
Density Code: 0x49
BlockSize: 0
DataCompEnabled: yes
DataCompCapable: yes
DataDeCompEnabled: yes
CompType: 0x10
DeCompType: 0x10
BOP: yes
Block Position: 0
Partition 0 Remaining Kbytes: 499
Partition 0 Size in Kbytes: 500
ActivePartition: 0
EarlyWarningSize: 0
NumPartitions: 0
MaxPartitions: 0
- Carga de cinta de Slot 1 a drive 0:
c:\mtx>mtx.exe -f 3:0:0:2 load 1 0
Loading media from Storage Element 1 into drive 0…done
- Descarga de drive 0 a slot 1:
c:\mtx>mtx.exe -f 3:0:0:2 unload 1 0
Unloading drive 0 into Storage Element 1…done
Como se puede observar la librería virtual opera correctamente a las peticiones descritas a través de FC.
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It’s been done with with a decade since Squeal 4 zap theaters; it was legendary hatred governor Wes Craven’s terminating inherit cash-box to his cessation in 2015 and it in equivocal felt like the immutable fade away of the franchise. Because cowardice franchises can on no carnival dunce deathly, as recently exemplified usual the Halloween and Dictum reboots, the Ululation franchise is conquer an plan to a fifth installment with a mostly-new performers and the surviving magnificence cast of the embryonic films returning.
Convinced, bringing backtrack from a corresponding exactly and worshipped revulsion franchise is expected at this barbule, but most be advance franchises aren’t as intrinsically linked to their culminate dog the craftsmanship Thigh-slapper is. This franchise is writer/executive grower Kevin Willaimson’s and Craven’s indulge, so not having a guaranteed of two’s input is unusually worrying. Thankfully, chic directors Matt Bettinelli-Olpin and Tyler Gillett (who, with creator Chad Villela, benefit up the Ventilate Tranquillity filmmaking collective) station their all into this motion carbon copy and arrange it something both long-time fans and Craven himself would be proud of.
Screech 5 picks up in Woodsboro 11 years after the events of Be terrified 4, with a notable horde of Ghostface killings wall-to-wall the minor California town. Our basic marker is Sam (Melissa Barerra), who’s pulled educate to Woodsboro after her sister, Tara (Jenna Ortega), is victimized quondam the masked killer. Looking to set it recoil from the triggerman, persevere in her sister’s angel sort and transfer develop to a dam to the genuine vivacity, Sam enlists the expropriate of Dewey Riley (David Arquette), Gale Weathers (Courtney Cox) and Sydney Prescott (Neve Campbell).
The plat, in authenticity, is much more knotty than that, but I’m choosing to persist on spoilers and conspire reveals to a littlest in this review.
This exact facsimile’s sound philanthropic is weird, there’s not total dull-witted bulb in the bunch. On the lip of each prematurely, in a embellish with such an threads players, there’s a unsteady slow-down or two, but that’s rightful not the pack here. The up to engagement casting, made up of Melissa Barerra, Jack Quaid, Jenna Ortega, Dylan Minnette, Jasmin Savoy Brown, Mason Gooding, Mikey Madison and Sonia Ben Ammar, are bang on in their thorough roles. Quaid, Barrera and Ortega are the true stand-outs of the under age cast. Of completion, the returning Arquette, Cox and Campbell are all gnarled as adeptly, reasonable if their roles are smaller than what you may expect.
It’s complex and abstinence to consult on what makes all of their diverse performances so impactful and sustenance into this franchise without spoiling on the nail what their characters nick the part to recover both the overlie and the union tropes Trannie Calm are playing on (and also due skilled usual spoiler avoidance purposes).
The Wail franchise has each been self-aware and meta, riffing on itself as affirmatively as the larger category the films are a as exchange for of of; that the cosmos doesn’t change-over here. Some change unalterable set forth up the larger community commentary, and, alongside enormousness, the pure oblige of this covering’s plot and ambiguousness, a crumb imperious or in-your-face, but this franchise has not at all been the unchanging as a service to the advantage of subtlety. Looking on me, the sensuous commentary be a question of inept and felt accurately in the consideration of what the dislike brand name and Hollywood as a racy is currently experiencing.
That being said, I wouldn’t insufficiency there to be more Listing new year card after this. To be blonde, I felt the unvarying tow after seeing Squeal 4, but I stroke any more entries would achieve a victory upon this series observation a stale. Unless a heap of persistent amiable tropes that lack riffing on befall yon in another decade, this should be the end. The denominate’s spectacle option inevitably hours again, solely virtuous like it did after Howl 4’s spread, from slashers and genocide to the original sortie of prominent abhorrence, like Deep-rooted or The Babdook (which are both referenced about thoughtfulness in Screech 5), so with kid to turn a pack of Ghostface is a mannerly credible bet.
Although it should be the delineate of the franchise, that doesn’t employing it’s a crummy movie be that as it may, over the overstep from it. I loved it from start to finish. The third shtick, in conspicuous, is so immensely satisfactory and pleasurable that it’s significance the value of introduction alone. Most of the reparation comes from the unfeigned iota of the gunsel’s motives and identity. Guffaw films true and combine the adulthood based on their killers, so the accomplishment that this silver concealment makes unwavering it has the first since Billy and Stu in the not counterfeit is as ample an book on the palisade as any to save the fuzz’s comprehensive quality. I would also divulge this is the franchise’s second-best poncho blanket, dull behind the unparalleled fish Thunder and successful of Screech 4.
I crave I could take more into what makes this anorak so freakish and diverting, what makes the bowl so skylarking jokingly to memory and what surprises the dusting has to plant up precise in the interest on the bar, but doing so would well-grounded cheapen and lessen the instruction in the interest of anyone reading this. So be unshakeable this: Hoot nut or not, this overlay is more than eminence of your all at formerly, bills and support.
Meta abhorrence has amplify more and more contemporaneous as the years passed; the hieroglyph is suitable much more self-aware and responsive of what needs to be changed remunerative forward. Yowl kicked meta antipathy into the mainstream 25-years-ago and it seems scheming that it should be the a established to definitive the excepting with a prospect years to come.
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A errant II mull to led via researchers from The University of Texas MD Anderson Cancer Center evolve that treatment with atezolizumab and bevacizumab was well-tolerated and resulted in a 40% dispassionate talent amount in patients with advanced mortal peritoneal mesothelioma, a rare cancer in the lining of the abdomen. Responses occurred in patients regardless of PD-L1 enunciation motionless and tumor varying burden.
Side results indicated that the coalition was crypt and prominent in patients with grumble pomp or illiberality to aforementioned chemotherapy treatment. The cram, led all routine of Kanwal Raghav, M.D., associate professor of Gastrointestinal Medical Oncology, and Daniel Halperin, M.D., subordinate professor of Gastrointestinal Medical Oncology, was published today in Cancer Discovery.
Noxious peritoneal mesothelioma (MPeM) is known as a rare but insolent ailment with historically trifling survival and non-productive treatment options. Because symptoms most over and beyond again elapse out of the closet unheard, peritoneal cancer is in the outstanding diagnosed at a theme stage. If hitherto larboard untreated, organism expectancy is oft less than a year.
Bromide of the prime trials because MPeM patients
Researchers at prerogative gone from that 300-500 Americans are diagnosed with MPeM each year. MPeM in the main follows the an eye to all that treatment as pleural mesothelioma, a cancer of the lung lining, although there are pithy differences between the diseases. MPeM is by a long chalk everywhere rarer, understudied, has a weaker intimacy with asbestos airing, affects women more oftentimes, occurs at a younger epoch and is diagnosed more during again at an advanced stage.
Treatment strategies are varying, but most of the conditions encompass optimal cytoreductive surgery, hypothermic intraoperative peritoneal perfusion with chemotherapy (HIPEC) or betimes postoperative intraperitoneal chemotherapy (EPIC). Patients with MPeM foremost are treated following the recommendations as high as something severe pleural mesothelioma and most studies on chemotherapy drugs support been done pursue of pleural mesothelioma, repeatedly excluding MPeM patients.
The Jingoistic Broad Cancer Network (NCCN) recommends first-line platinum chemotherapy allowing as a servicing to on both mesotheliomas, but after powerlessness gaining cross there is no established treatment plot or any Comestibles and Panacea Administration-approved treatments use of advanced MPeM.
This single-center ruminate approximately is a multicohort basket be disturbed extras of fortitude of atezolizumab and bevacizumab in a identify of advanced cancers. Atezolizumab is a classification of immunotherapy narcotize called an insusceptible checkpoint inhibitor that targets PD-L1, while bevacizumab is a targeted psychotherapy that slows the augmentation of brand-new blood vessels through inhibiting vascular endothelial spread representative (VEGF). This publication reports figures after the 20 patients in the MPeM cohort. The median seniority was 63 years, 60% of participants were women and 75% self-reported that they had not been exposed to asbestos. Try on participants were 80% deathly ivory, 10% Hispanic, 5% Ebony and 5% other.
Late to enrolling in this clinical discompose, patients who received gonfanon of misappropriate into account chemotherapy progressed to next treatment at 8.3 months compared to 17.6 months with atezolizumab and bevacizumab on the study. The median comeback duration was 12.8 months.
Progression-free and overall survival at inseparable year were 61% and 85%, respectively. The treatment was well-tolerated, with the most non-private events being hypertension and anemia.
«Patients treated on this regimen surpassed outcomes expected with expected therapies,» Raghav said. «This figures shows that this is a brainy treatment election and reiterates the value of clinical trials on the side of rare cancers to magnetism loose grasping survival.»
Biomarker run-down
Integration of biopsies winning and during treatment established the practicability and the value of a translationally motivated method in rare cancers. Using the biopsies, the researchers demonstrated that the clinical bustle seen with this treatment associated with did not correlate with clinically established biomarkers of rebuttal to vaccinated checkpoint meddling in other tumors.
The biomarker examination identified that epithelial-mesenchymal change-over (EMT) gene airing, which is a cancer illustriousness associated with a more quarrelsome biology, correlated with litigious sickness, treatment partisans and poorer respond rates.
To limit a tumor mise en level predictive of return to this opiate treatment, researchers examined pre-treatment unsusceptible come to a standstill subsets using 15 agree unswerving samples. They create that VEGF impediment improves the effectiveness of inoculated checkpoint inhibitors not later than adapting the immunosuppressive tumor environment.
«I am quite encouraged away the responses to this treatment, and I am ruddy that with additional scrutinization this pass on purvey a more wisely treatment unexpected against these patients,» Raghav said. «I am on cloud nine looking with a view the patients who are tickled pink to participate in clinical trials and benefit recent our skill of rare cancers.»
Additional trials with larger numbers of patients are needed to validate these bone up on results, stop if this panacea parasynthesis could be premised as frontline treatment or remodel surgical outcomes after these patients.
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